RNA: a double-edged sword in genome maintenance
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-020-0263-7
Abstract: All organisms must safeguard the integrity of their DNA to avoid deleterious consequences of genome instability, which have been linked to human diseases such as autoimmune disorders, neurodegenerative diseases and cancer. Traditionally, genome maintenance has… read more here.
Keywords: genome maintenance; maintenance; rna double; genome instability ... See more keywords
A novel form of RNA double helix based on G·U and C·A+ wobble base pairing.
Sign Up to like & getrecommendations! Published in 2018 at "RNA"
DOI: 10.1261/rna.064048.117
Abstract: Wobble base pairs are critical in various physiological functions and have been linked to local structural perturbations in double-helical structures of nucleic acids. We report a 1.38-Å resolution crystal structure of an antiparallel octadecamer RNA… read more here.
Keywords: rna; rna double; base pairs; wobble base ... See more keywords