SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103861
Abstract: Background Since late 2019, SARS-CoV-2 infection has resulted in COVID-19 accompanied by diverse clinical manifestations. However, the underlying mechanism of how SARS-CoV-2 interacts with host and develops multiple symptoms is largely unexplored. Methods Bioinformatics analysis… read more here.
Keywords: sars cov; sequence; hyaluronan; rna elements ... See more keywords
Zebrafish embryogenesis - A framework to study regulatory RNA elements in development and disease.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.01.008
Abstract: Post-transcriptional gene regulation through the recognition of specific elements in mRNAs is an important determinant of gene expression. The cis elements are recognised by RNA binding proteins (RBPs) and/or small non-coding RNAs, which then orchestrate… read more here.
Keywords: development disease; rna elements; zebrafish embryogenesis; study ... See more keywords
Therapy based on functional RNA elements
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abj7969
Abstract: Fragments of long noncoding RNAs show potential in treating a metabolic disorder in mice Over the past several years, advances in RNA sequencing have led to an increased appreciation of the prevalence and function of… read more here.
Keywords: therapy based; rna elements; functional rna; lncrna ... See more keywords