Mechanisms of RNA export and nuclear retention
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1755
Abstract: With the identification of huge amount of noncoding RNAs in recent years, the concept of RNA localization has extended from traditional mRNA export to RNA export of mRNA and ncRNA as well as nuclear retention… read more here.
Keywords: mechanisms rna; nuclear retention; rna export; sequence dependent ... See more keywords
The RNA export factor TbMex67 connects transcription and RNA export in Trypanosoma brucei and sets boundaries for RNA polymerase I.
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DOI: 10.1093/nar/gkad251
Abstract: Abstract TbMex67 is the major mRNA export factor known to date in trypanosomes, forming part of the docking platform within the nuclear pore. To explore its role in co-transcriptional mRNA export, recently reported in Trypanosoma… read more here.
Keywords: tbmex67; transcription; rna export; factor ... See more keywords
The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions
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DOI: 10.1371/journal.pbio.3001940
Abstract: Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability. In this study, we… read more here.
Keywords: cag repeat; rna export; repeat; cag ... See more keywords