Circular RNA expression profiles and bioinformatics analysis in ovarian endometriosis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.756
Abstract: Circular RNAs (circRNAs) with miRNA response elements (MREs) could function as competing endogenous RNA (ceRNA) in regulating gene expression, thus playing vital roles in pathogenesis and progression of many diseases. However, the function of circRNAs… read more here.
Keywords: endometriosis; ovarian endometriosis; circular rna; expression ... See more keywords
Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1421-1
Abstract: Functional genomics applied to the study of RNA expression profiles identified several abnormal molecular processes in experimental prion disease. However, only a few similar studies have been carried out to date in a naturally occurring… read more here.
Keywords: expression profiles; analysis; value; disease ... See more keywords
Micro RNA expression profile in pregnant women complicated fetuses with muscular ventricular septal defects: 236
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.257
Abstract: 236 Micro RNA expression profile in pregnant women complicated fetuses with muscular ventricular septal defects Sifa Turan, Ozhan M. Turan, Hong Song, Lindsey Seger, Pragati Sidh, Harman Christopher, Loren p. Thompson University of Maryland, School… read more here.
Keywords: medicine; expression profile; ventricular septal; expression ... See more keywords
RNA expression profiles and regulatory networks in human right ventricular hypertrophy due to high pressure load
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102232
Abstract: Summary Right ventricular hypertrophy (RVH) occurs in high pressure afterload, e.g., tetralogy of Fallot/pulmonary stenosis (TOF/PS). Such RVH is associated with alterations in energy metabolism, neurohormonal and epigenetic dysregulation (e.g., microRNA), and fetal gene reprogramming… read more here.
Keywords: rvh; ventricular hypertrophy; right ventricular; expression ... See more keywords
Genetically predicted complement component 4A expression: effects on memory function and middle temporal lobe activation
Sign Up to like & getrecommendations! Published in 2018 at "Psychological Medicine"
DOI: 10.1017/s0033291717002987
Abstract: Abstract Background The longstanding association between the major histocompatibility complex (MHC) locus and schizophrenia (SZ) risk has recently been accounted for, partially, by structural variation at the complement component 4 (C4) gene. This structural variation… read more here.
Keywords: rna expression; complement component; expression; memory ... See more keywords
T7 Polymerase Expression of Guide RNAs in vivo Allows Exportable CRISPR-Cas9 Editing in Multiple Yeast Hosts.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.7b00461
Abstract: Efficient guide RNA expression often limits CRISPR-Cas9 implementation in new hosts. To address this limitation in fungal systems, we demonstrate the utility of a T7 polymerase system to effectively express sgRNAs. Initially, we developed a… read more here.
Keywords: guide rna; crispr cas9; polymerase expression; guide ... See more keywords
Using protein turnover to expand the applications of transcriptomics
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-83886-7
Abstract: RNA expression and protein abundance are often at odds when measured in parallel, raising questions about the functional implications of transcriptomics data. Here, we present the concept of persistence, which attempts to address this challenge… read more here.
Keywords: protein; protein turnover; turnover expand; protein abundance ... See more keywords
Potential role of a clinical, taxonomical classification and RNA expression integrated signature to predict response to neoadjuvant platinum-based chemotherapy in muscle-invasive bladder cancer (MIBC) patients
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz249.030
Abstract: Abstract Background Neoadjuvant chemotherapy (NAC) followed by cystectomy is the standard of care in MIBC patients, although a limited survival benefit has been obtained compared with cystectomy alone. Pathologic response has been associated with survival,… read more here.
Keywords: mibc patients; rna expression; response; signature ... See more keywords
Temperature-dependent Small RNA Expression Depends on Wild Genetic Backgrounds of Caenorhabditis briggsae
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac218
Abstract: Geographically distinct populations can adapt to the temperature conditions of their local environment, leading to temperature-dependent fitness differences between populations. Consistent with local adaptation, phylogeographically distinct Caenorhabditis briggsae nematodes show distinct fitness responses to temperature.… read more here.
Keywords: temperature dependent; rna expression; briggsae; expression ... See more keywords
Widespread Down-Regulation of Cardiac Mitochondrial and Sarcomeric Genes in Patients With Sepsis*
Sign Up to like & getrecommendations! Published in 2017 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000002207
Abstract: Objectives: The mechanism(s) for septic cardiomyopathy in humans is not known. To address this, we measured messenger RNA alterations in hearts from patients who died from systemic sepsis, in comparison to changed messenger RNA expression… read more here.
Keywords: heart; energy production; septic cardiomyopathy; messenger rna ... See more keywords
Genetic alterations, RNA expression profiling and DNA methylation of HMGB1 in malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17454
Abstract: The high mobility group box 1 (HMGB1) is a potential biomarker and therapeutic target in various human diseases. However, a systematic, comprehensive pan‐cancer analysis of HMGB1 in human cancers remains to be reported. This study… read more here.
Keywords: profiling dna; rna expression; dna methylation; expression ... See more keywords