MET-2-Dependent H3K9 Methylation Suppresses Transgenerational Small RNA Inheritance
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DOI: 10.1016/j.cub.2017.03.008
Abstract: In C. elegans, alterations to chromatin produce transgenerational effects, such as inherited increase in lifespan and gradual loss of fertility. Inheritance of histone modifications can be induced by double-stranded RNA-derived heritable small RNAs. Here, we show… read more here.
Keywords: small rna; h3k9 methylation; inheritance; rna inheritance ... See more keywords
Differential nuclear import regulates nuclear RNA inheritance following mitosis
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e23-01-0004
Abstract: Mitosis results in a dramatic reorganization of chromatin structure to promote chromosome compaction and segregation to daughter cells. Consequently, mitotic entry is accompanied by transcriptional silencing and removal of most chromatin-bound RNA from chromosomes. As… read more here.
Keywords: mitosis; following mitosis; chromatin; rna inheritance ... See more keywords