Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies.
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DOI: 10.1002/adhm.201601041
Abstract: It has been nearly two decades since RNA-interference (RNAi) was first reported. While there are no approved clinical uses, several phase II and III clinical trials suggest the great promise of RNAi therapeutics. One challenge… read more here.
Keywords: local sustained; hydrogels local; rna interference; rnai ... See more keywords
Innovations in Biomaterial Design toward Successful RNA Interference Therapy for Cancer Treatment.
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DOI: 10.1002/adhm.202100350
Abstract: Gene regulation using RNA interference (RNAi) therapy has been developed as one of the frontiers in cancer treatment. The ability to tailor the expression of genes by delivering synthetic oligonucleotides to tumor cells has transformed… read more here.
Keywords: cancer; therapy; rna interference; cancer treatment ... See more keywords
Bubbled RNA‐Based Cargo for Boosting RNA Interference
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DOI: 10.1002/advs.201600523
Abstract: As ribonucleic acid (RNA) nanotechnology has advanced, it has been applied widely in RNA‐based therapeutics. Among the range of approaches, enzymatically synthesized RNA structures for inducing RNA interference in cancer cells have potential for silencing… read more here.
Keywords: rna based; bubbled rna; rna interference; based cargo ... See more keywords
Knockdown of Helicoverpa armigera protease genes affects its growth and mortality via RNA interference.
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DOI: 10.1002/arch.21840
Abstract: Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae), the cotton bollworm, is a destructive pest which is famous for its resistance to a variety of insecticides. RNA interference is a posttranscriptional gene silencing mechanism that has become a… read more here.
Keywords: helicoverpa armigera; rna interference; mortality; armigera ... See more keywords
Gene silencing in non‐model insects: Overcoming hurdles using symbiotic bacteria for trauma‐free sustainable delivery of RNA interference
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DOI: 10.1002/bies.201600247
Abstract: Insight into animal biology and development provided by classical genetic analysis of the model organism Drosophila melanogaster was an incentive to develop advanced genetic tools for this insect. But genetic systems for the over one… read more here.
Keywords: insects; delivery; rna interference; model ... See more keywords
RNA interference: Promising approach for breast cancer diagnosis and treatment
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DOI: 10.1002/cbin.11979
Abstract: Today, cancer is one of the main health‐related challenges, and in the meantime, breast cancer (BC) is one of the most common cancers among women, with an alarming number of incidences and deaths every year.… read more here.
Keywords: diagnosis treatment; breast cancer; cancer; rna interference ... See more keywords
Inference from RNA interference: Suggestions to our authors
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32641
Abstract: Those of you who read Nature must have been astounded in 2008 about an article stating that “Non-targeted (against nonmammalian genes) and targeted (against Vegfa or Vegfr1) siRNA suppressed choroidal neovascularization via cell-surface toll-like receptor… read more here.
Keywords: inference rna; rna interference; suggestions authors; interference suggestions ... See more keywords
Injecting RNA interference lentiviruses targeting the muscarinic 3 receptor gene into the bladder wall inhibits neurogenic detrusor overactivity in rats with spinal cord injury
Sign Up to like & getrecommendations! Published in 2019 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.23894
Abstract: To investigate the effects of injecting RNA interference (RNAi) lentiviruses targeting the muscarinic 3 (M3) receptor gene into the bladder wall on bladder activity in rats with spinal cord injury (SCI). read more here.
Keywords: injecting rna; bladder; rna interference; targeting muscarinic ... See more keywords
Delivery strategies: RNA interference in agriculture and human health.
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DOI: 10.1002/ps.4341
Abstract: Crop protection through expression of introduced insecticidal proteins is a well-established technique. Modifications of endogenous gene expression have also been used successfully to produce safe and effective agrochemical products. The existing gene expression regulatory apparatus… read more here.
Keywords: agriculture; strategies rna; delivery; rna interference ... See more keywords
Suppression of Bta11975, an α-glucosidase, by RNA interference reduces transmission of Tomato chlorosis virus by Bemisia tabaci.
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DOI: 10.1002/ps.6572
Abstract: BACKGROUND Tomato chlorosis virus (ToCV) is mainly vectored by Bemisia tabaci (B. tabaci) in China, which has a worldwide distribution, and greatly reduces the yields of tomato and other vegetables. At present, control of ToCV… read more here.
Keywords: bta11975; bta11975 gene; transmission; tabaci ... See more keywords
Vacuolar (H+ )-ATPase subunit c is essential for the survival and systemic RNA interference response in Locusta migratoria.
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DOI: 10.1002/ps.6774
Abstract: BACKGROUND Vacuolar (H+ )-ATPase (V-ATPase) is a multi-subunit enzyme that hydrolyzes ATP to transport protons across a cellular membrane, and it plays an important role in numerous biological processes, including in growth, development and immune… read more here.
Keywords: vacuolar atpase; locusta migratoria; rna interference; lmv atpase ... See more keywords