RNA m6A methylation in cancer
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DOI: 10.1002/1878-0261.13326
Abstract: N6‐methyladenosine (m6A) is one of the most abundant internal modifications in eukaryotic messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic RNA modification that has been observed in both internal coding… read more here.
Keywords: m6a methylation; cancer; rna m6a;
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming
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DOI: 10.1038/s41467-021-21514-8
Abstract: N6-methyladenosine (m6A) is a reversible mRNA modification that has been shown to play important roles in various biological processes. However, the roles of m6A modification in macrophages are still unknown. Here, we discover that ablation… read more here.
Keywords: growth metastasis; macrophage; growth; rna m6a ... See more keywords
Marking RNA: m6A writers, readers, and functions in Arabidopsis
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DOI: 10.1093/jmcb/mjz085
Abstract: Abstract N6-methyladenosine (m6A) emerges as an important modification in eukaryotic mRNAs. m6A has first been reported in 1974, and its functional significance in mammalian gene regulation and importance for proper development have been well established.… read more here.
Keywords: m6a modification; m6a writers; marking rna; m6a ... See more keywords
MP01-05 CIRCXPO1-MEDIATED RNA M6A MODIFICATION PROMOTES THE PROGRESSION OF BLADDER CANCER
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DOI: 10.1097/ju.0000000000000815.05
Abstract: INTRODUCTION AND OBJECTIVE:Circular RNAs (circRNAs) have been identified as a novel class of endogenous noncoding RNA and characterized by its closed circular structure. The roles of circRNAs as th... read more here.
Keywords: circxpo1 mediated; modification promotes; m6a modification; rna m6a ... See more keywords
RNA m6A Methyltransferase Mettl3 Regulates Spatial Neural Patterning in Xenopus laevis
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DOI: 10.1128/mcb.00104-21
Abstract: N6-methyladenosine (m6A) is the most prevalent internal RNA modification and has a widespread impact on mRNA stability and translation. Methyltransferase-like 3 (Mettl3) is a methyltransferase responsible for RNA m6A modification, and it is essential for… read more here.
Keywords: neural patterning; spatial neural; rna m6a; methyltransferase ... See more keywords
Abstract 6006: RNA m6A methylation relay the oncogenic flow from DNA methylationto gene expression of ANKRD13B
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6006
Abstract: Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. More comprehensive studies of key molecular alterations in CRC progression were urgent. DNA methylation promotes tumor progression. However,… read more here.
Keywords: methylation; expression; rna m6a; colorectal cancer ... See more keywords
RNA m6A modifications in mammalian gametogenesis and pregnancy.
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DOI: 10.1530/rep-22-0112
Abstract: The epitranscriptome is defined as the collection of post-transcriptional chemical modifications of RNA in a cell. RNA methylation refers to the chemical post-transcriptional modification of RNA by selectively adding methyl groups under the catalysis of… read more here.
Keywords: m6a modifications; gametogenesis; rna; rna m6a ... See more keywords
The role of RNA m6A methylation in lipid metabolism
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DOI: 10.3389/fendo.2022.866116
Abstract: The m6A methylation is the most numerous modification of mRNA in mammals, coordinated by RNA m6A methyltransferases, RNA m6A demethylases, and RNA m6A binding proteins. They change the RNA m6A methylation level in their specific… read more here.
Keywords: m6a methylation; lipid metabolism; rna m6a;
Corrigendum: RNA m6A Methylation Regulators Multi-Omics Analysis in Prostate Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.845413
Abstract: [This corrects the article DOI: 10.3389/fgene.2021.768041.]. read more here.
Keywords: regulators multi; multi omics; rna m6a; corrigendum rna ... See more keywords
Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy
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DOI: 10.3389/fgene.2022.859727
Abstract: Objective: To investigate the relationship among the gut microbiome, serum metabolomic profile and RNA m6A methylation in patients with sepsis-associated encephalopathy (SAE), 16S rDNA technology, metabolomics and gene expression validation were applied. Methods: Serum and… read more here.
Keywords: serum; rna m6a; group; gut microbiome ... See more keywords
RNA m6A methylation regulators in endometrial cancer (Review)
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DOI: 10.3892/ijo.2022.5445
Abstract: As one of the three major malignant tumor types of the female reproductive system, endometrial cancer (EC) is the most prevalent gynecologic cancer in developed countries. In recent years, the incidence of EC has increased… read more here.
Keywords: m6a methylation; methylation; endometrial cancer; rna m6a ... See more keywords