p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03417-3
Abstract: Ultraviolet (UV) light radiation induces the formation of bulky photoproducts in the DNA that globally affect transcription and splicing. However, the signaling pathways and mechanisms that link UV-light-induced DNA damage to changes in RNA metabolism… read more here.
Keywords: dna damage; light induced; p38 mk2; induced dna ... See more keywords
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab680
Abstract: Abstract Gene deletion and gene expression alteration can lead to growth defects that are amplified or reduced when a second mutation is present in the same cells. We performed 154 genetic interaction mapping (GIM) screens… read more here.
Keywords: large scale; rna metabolism; gene; genetic interaction ... See more keywords
Analysis of RNA Metabolism in Fission Yeast.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.top079798
Abstract: Here we focus on the biogenesis and function of messenger RNA (mRNA) in fission yeast cells. Following a general introduction that also briefly touches on other classes of RNA, we provide an overview of methods… read more here.
Keywords: fission; metabolism fission; rna metabolism; analysis rna ... See more keywords
Inactivation of RNase P in Escherichia coli significantly changes post-transcriptional RNA metabolism.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular microbiology"
DOI: 10.1111/mmi.14808
Abstract: Ribonuclease P (RNase P), which is required for the 5'-end maturation of tRNAs in every organism, has been shown to play a limited role in other aspects of RNA metabolism in Escherichia coli. Using RNA-sequencing… read more here.
Keywords: escherichia coli; rna metabolism; post transcriptional; rnase ... See more keywords
Toward Time-Resolved Analysis of RNA Metabolism in Archaea Using 4-Thiouracil
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.00286
Abstract: Archaea are widespread organisms colonizing almost every habitat on Earth. However, the molecular biology of archaea still remains relatively uncharacterized. RNA metabolism is a central cellular process, which has been extensively analyzed in both bacteria… read more here.
Keywords: rna metabolism; analysis rna; rna; time ... See more keywords
Regulation of SUMOylation on RNA metabolism in cancers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1137215
Abstract: Post-translational modifications of proteins play very important roles in regulating RNA metabolism and affect many biological pathways. Here we mainly summarize the crucial functions of small ubiquitin-like modifier (SUMO) modification in RNA metabolism including transcription,… read more here.
Keywords: regulation sumoylation; metabolism; sumoylation rna; rna metabolism ... See more keywords
The Regulatory Role of RNA Metabolism Regulator TDP-43 in Human Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.755096
Abstract: TAR-DNA-binding protein-43 (TDP-43) is a member of hnRNP family and acts as both RNA and DNA binding regulator, mediating RNA metabolism and transcription regulation in various diseases. Currently, emerging evidence gradually elucidates the crucial role… read more here.
Keywords: tdp human; metabolism; role; rna metabolism ... See more keywords
Chloroplast- or Mitochondria-Targeted DEAD-Box RNA Helicases Play Essential Roles in Organellar RNA Metabolism and Abiotic Stress Responses
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.00871
Abstract: The yields and productivity of crops are greatly diminished by various abiotic stresses, including drought, cold, heat, and high salinity. Chloroplasts and mitochondria are cellular organelles that can sense diverse environmental stimuli and alter gene… read more here.
Keywords: metabolism; rna metabolism; organellar rna; dead box ... See more keywords
Role of C14orf166 in viral infection and RNA metabolism and its relationship with cancer (Review).
Sign Up to like & getrecommendations! Published in 2021 at "Molecular medicine reports"
DOI: 10.3892/mmr.2021.12039
Abstract: Chromosome 14 open reading frame 166 (C14orf166) encodes a 28‑kDa nuclear and cytoplasmic protein that is involved in viral infection, RNA metabolism, and centrosome structure. It binds to the polymerase acidic protein subunit of the influenza A virus,… read more here.
Keywords: c14orf166; infection; viral infection; cancer ... See more keywords
RNA Metabolism in T Lymphocytes
Sign Up to like & getrecommendations! Published in 2022 at "Immune Network"
DOI: 10.4110/in.2022.22.e39
Abstract: RNA metabolism plays a central role in regulating of T cell-mediated immunity. RNA processing, modifications, and regulations of RNA decay influence the tight and rapid regulation of gene expression during T cell phase transition. Thymic… read more here.
Keywords: metabolism lymphocytes; metabolism; rna metabolism;