Detecting RNA–RNA interactome
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1715
Abstract: The last decade has seen a robust increase in various types of novel RNA molecules and their complexity in gene regulation. RNA molecules play a critical role in cellular events by interacting with other biomolecules,… read more here.
Keywords: rna interactome; rna molecules; rna; detecting rna ... See more keywords
Evolving methods for rational de novo design of functional RNA molecules.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.04.022
Abstract: Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient alternative to experimental… read more here.
Keywords: evolving methods; rna molecules; methods rational; novo design ... See more keywords
Mineral surfaces select for longer RNA molecules.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc10319d
Abstract: We report empirically and theoretically that multiple prebiotic minerals can selectively accumulate longer RNAs, with selectivity enhanced at higher temperatures. We further demonstrate that surfaces can be combined with a catalytic RNA to form longer… read more here.
Keywords: select longer; mineral surfaces; longer rna; rna molecules ... See more keywords
Mechanisms of catalytic RNA molecules.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Society transactions"
DOI: 10.1042/bst20200465
Abstract: Ribozymes are folded catalytic RNA molecules that perform important biological functions. Since the discovery of the first RNA with catalytic activity in 1982, a large number of ribozymes have been reported. While most catalytic RNA… read more here.
Keywords: mechanisms catalytic; catalytic rna; rna molecules;
Genetically Modified Organism-Free RNA Interference: Exogenous Application of RNA Molecules in Plants1[OPEN]
Sign Up to like & getrecommendations! Published in 2019 at "Plant Physiology"
DOI: 10.1104/pp.19.00570
Abstract: The latest advances in the field exogenous application of RNA molecules in plants help to protect and modify them through RNA interference (RNAi). read more here.
Keywords: rna molecules; rna interference; rna; application rna ... See more keywords
ANGEL2 is a member of the CCR4 family of deadenylases with 2′,3′-cyclic phosphatase activity
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aba9763
Abstract: Deadenylating RNA molecules Transfer RNA (tRNA) and messenger RNA molecules often acquire a terminal 2′,3′-cyclic phosphate group when processed in the cell. These cyclic phosphates provide attachment points for tRNA ligases and must be removed… read more here.
Keywords: phosphatase; rna; rna molecules; transfer rna ... See more keywords
Integration of RNA molecules data with prior-knowledge driven Joint Deep Semi-Negative Matrix Factorization for heart failure study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.967363
Abstract: Heart failure (HF) is the main manifestation of cardiovascular disease. Recent studies have shown that various RNA molecules and their complex connections play an essential role in HF’s pathogenesis and pathological progression. This paper aims… read more here.
Keywords: prior knowledge; rna molecules; heart failure; knowledge driven ... See more keywords
RNA World Modeling: A Comparison of Two Complementary Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Entropy"
DOI: 10.3390/e24040536
Abstract: Simple Summary Despite years of dedicated research, scientists are still not sure what the first ”living” cell would have looked like. One of the most well-known hypotheses is the RNA world hypothesis, which assumes that,… read more here.
Keywords: world; rna world; modeling comparison; comparison two ... See more keywords
Alternative RNA Conformations: Companion or Combatant
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13111930
Abstract: RNA molecules, in one form or another, are involved in almost all aspects of cell physiology, as well as in disease development. The diversity of the functional roles of RNA comes from its intrinsic ability… read more here.
Keywords: companion combatant; rna molecules; rna; conformations companion ... See more keywords
Towards an Ideal In Cell Hybridization-Based Strategy to Discover Protein Interactomes of Selected RNA Molecules
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020942
Abstract: RNA-binding proteins are crucial to the function of coding and non-coding RNAs. The disruption of RNA–protein interactions is involved in many different pathological states. Several computational and experimental strategies have been developed to identify protein… read more here.
Keywords: cell hybridization; selected rna; rna molecules; rna ... See more keywords
Asymmetric Inheritance of Cell Fate Determinants: Focus on RNA
Sign Up to like & getrecommendations! Published in 2019 at "Non-Coding RNA"
DOI: 10.3390/ncrna5020038
Abstract: During the last decade, and mainly primed by major developments in high-throughput sequencing technologies, the catalogue of RNA molecules harbouring regulatory functions has increased at a steady pace. Current evidence indicates that hundreds of mammalian… read more here.
Keywords: inheritance; rna molecules; asymmetric inheritance; fate ... See more keywords