Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14780-5
Abstract: Paclitaxel is widely used in cancer treatments, but poor water-solubility and toxicity raise serious concerns. Here we report an RNA four-way junction nanoparticle with ultra-thermodynamic stability to solubilize and load paclitaxel for targeted cancer therapy.… read more here.
Keywords: thermostable rna; rna nanoparticles; cancer; cancer therapy ... See more keywords
Preparation, characterisation, and in vitro cancer‐suppression function of RNA nanoparticles carrying miR‐301b‐3p Inhibitor
Sign Up to like & getrecommendations! Published in 2023 at "IET Nanobiotechnology"
DOI: 10.1049/nbt2.12120
Abstract: Abstract Background Multidrug resistance is the biggest barrier on the way to chemotherapy for lung adenocarcinoma (LUAD). For some LUAD patients with cisplatin (DDP) resistance and poor prognoses, the authors put forward RNA nanoparticles (NPs)… read more here.
Keywords: mir 301b; rna nanoparticles; mir; 301b inhibitor ... See more keywords