Cell block‐based RNA next generation sequencing for detection of gene fusions in lung adenocarcinoma: An institutional experience
Sign Up to like & getrecommendations! Published in 2022 at "Cytopathology"
DOI: 10.1111/cyt.13175
Abstract: Targeted therapy is an important part of the treatment of lung adenocarcinoma. Tests for EGFR mutation, ALK, ROS1, RET and NTRK gene fusions are needed to make a treatment decision. These gene fusions are traditionally… read more here.
Keywords: lung adenocarcinoma; gene fusions; rna next; next generation ... See more keywords
Mapping actionable pathways and mutations in brain tumours using targeted RNA next generation sequencing
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0826-z
Abstract: Many biology-based precision drugs are available that neutralize aberrant molecular pathways in cancer. Molecular heterogeneity and the lack of reliable companion diagnostic biomarkers for many drugs makes targeted treatment of cancer inaccurate for many individuals.… read more here.
Keywords: targeted rna; next generation; mapping actionable; rna next ... See more keywords