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   Articles with "rna packaging" as a keyword



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Identification of the initial nucleocapsid recognition element in the HIV-1 RNA packaging signal

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recommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2008519117

Abstract: Significance Understanding the molecular determinants of retroviral genome packaging is important for drug discovery and development of vectors for gene delivery. We show that the HIV-1 leader, which contains the RNA elements necessary for genome… read more here.

Keywords: rna packaging; rna; hiv; leader ... See more keywords
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Epitranscriptomic regulation of HIV-1 full-length RNA packaging

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recommendations! Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac062

Abstract: Abstract During retroviral replication, the full-length RNA serves both as mRNA and genomic RNA. However, the mechanisms by which the HIV-1 Gag protein selects the two RNA molecules that will be packaged into nascent virions… read more here.

Keywords: full length; length rna; rna; rna packaging ... See more keywords
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Revolution in an RNA-packaging capsid

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recommendations! Published in 2021 at "Science"

DOI: 10.1126/science.372.6547.1162-a

Abstract: Directed Evolution Artificial nucleocapsid proteins, which could be analogous to those used by viruses to package their genomes, are a promising way to protect and deliver RNAs. Using an escalating challenge by nucleases, Tetter et… read more here.

Keywords: microscopy; capsid; rna packaging; revolution rna ... See more keywords
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Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus

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recommendations! Published in 2018 at "Journal of Biomedical Science"

DOI: 10.1186/s12929-018-0449-x

Abstract: BackgroundMiddle East respiratory syndrome coronavirus (MERS-CoV) consists of a positive-sense, single-stranded RNA genome and four structural proteins: the spike, envelope, membrane, and nucleocapsid protein. The assembly of the viral genome into virus particles involves viral… read more here.

Keywords: nucleocapsid protein; rna packaging; assembly rna; packaging signal ... See more keywords
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Human Retrovirus Genomic RNA Packaging

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recommendations! Published in 2022 at "Viruses"

DOI: 10.3390/v14051094

Abstract: Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles. Retroviral RNA packaging requires RNA export of the unspliced genomic RNA from… read more here.

Keywords: genomic rna; human retrovirus; rna; retrovirus genomic ... See more keywords