Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity
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DOI: 10.1126/sciadv.abn9458
Abstract: The Down syndrome cell adhesion molecule 1 (Dscam1) gene can generate tens of thousands of isoforms via alternative splicing, which is essential for nervous and immune functions. Chelicerates generate approximately 50 to 100 shortened Dscam… read more here.
Keywords: rna pairing; homophilic binding; binding specificity; trans splicing ... See more keywords