EPCT-13. CMV PP65 RNA-PULSED DENDRITIC CELL VACCINES FOR PEDIATRIC GLIOBLASTOMA AND MEDULLOBLASTOMA: PHASE I TRIAL RESULTS
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.136
Abstract: Abstract BACKGROUND Recurrent medulloblastoma and malignant glioma are lethal tumors that are virtually incurable. The cytomegalovirus (CMV) antigen pp65 is ubiquitously expressed on medulloblastoma and malignant glioma but not on healthy brain. We evaluated autologous… read more here.
Keywords: pp65 rna; pp65; rna pulsed; cmv pp65 ... See more keywords
Breast cancer stem cell RNA-pulsed dendritic cells enhance tumor cell killing by effector T cells
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DOI: 10.3892/ol.2020.11338
Abstract: Cancer stem cells (CSCs) underpin the resistance of breast cancer (BC) cells to therapy. Dendritic cell (DC)-based treatment is efficacious and safe, but the efficiency of this technique for targeting CSCs in BC treatment requires… read more here.
Keywords: cell; effector cells; cancer; effector ... See more keywords