Functional diversity of Arabidopsis organelle‐localized RNA‐recognition motif‐containing proteins
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1420
Abstract: RNA‐Binding Proteins (RBPs) play key roles in plant gene expression and regulation. RBPs contain a variety of RNA‐binding motifs, the most abundant and most widespread one in eukaryotes is the RNA recognition motif (RRM). Many… read more here.
Keywords: containing proteins; rna; organelle localized; rna recognition ... See more keywords
The role of the protein–RNA recognition code in neurodegeneration
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03096-3
Abstract: MicroRNAs are small endogenous RNAs that pair and bind to sites on mRNAs to direct post-transcriptional repression. However, there is a possibility that microRNAs directly influence protein structure and activity, and this influence can be… read more here.
Keywords: protein; recognition code; code; proteins involved ... See more keywords
Integrated structural biology to unravel molecular mechanisms of protein-RNA recognition.
Sign Up to like & getrecommendations! Published in 2017 at "Methods"
DOI: 10.1016/j.ymeth.2017.03.015
Abstract: Recent advances in RNA sequencing technologies have greatly expanded our knowledge of the RNA landscape in cells, often with spatiotemporal resolution. These techniques identified many new (often non-coding) RNA molecules. Large-scale studies have also discovered… read more here.
Keywords: unravel molecular; protein rna; biology; rna recognition ... See more keywords
Monovalent Ionic Atmosphere Modulates the Selection of Suboptimal RNA Sequences by Splicing Factors' RNA Recognition Motifs
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.3c00110
Abstract: The U2AF2 splicing factor is involved in the RNA recognition of the pre-mRNA poly-pyrimidine signaling sequence. This protein contains two RRM domains connected by a flexible linker, which ensure the preferential selection of a poly-uridine… read more here.
Keywords: recognition; splicing factors; selection suboptimal; rna recognition ... See more keywords
Roles of the RGG Domain and RNA Recognition Motif of Nucleolin in G-Quadruplex Stabilization
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b04221
Abstract: G-quadruplexes have important biologic functions that are regulated by G-quadruplex-binding proteins. In particular, G-quadruplex structures are folded or unfolded by their binding proteins and affect transcription and other biologic functions. Here, we investigated the effect… read more here.
Keywords: nucleolin quadruplex; rgg domain; rna recognition; domain ... See more keywords
Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b05366
Abstract: Members of the heterogeneous nuclear ribonucleoprotein (hnRNP) F/H family are multipurpose RNA binding proteins that participate in most stages of RNA metabolism. Despite having similar RNA sequence preferences, hnRNP F/H proteins function in overlapping and,… read more here.
Keywords: nuclear ribonucleoprotein; rna; linker; quasi rna ... See more keywords
Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03920-7
Abstract: RNA-binding proteins regulate all aspects of RNA metabolism. Their association with RNA is mediated by RNA-binding domains, of which many remain uncharacterized. A recently reported example is the NHL domain, found in prominent regulators of… read more here.
Keywords: solutions rna; nhl domain; biology; rna recognition ... See more keywords
Structural basis of 3′-end poly(A) RNA recognition by LARP1
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac696
Abstract: Abstract La-related proteins (LARPs) comprise a family of RNA-binding proteins involved in a wide range of posttranscriptional regulatory activities. LARPs share a unique tandem of two RNA-binding domains, La motif (LaM) and RNA recognition motif… read more here.
Keywords: rna; rna recognition; poly rna; poly ... See more keywords
GLYCINE-RICH RNA-BINDING PROTEIN7 Potentiates Effector-Triggered Immunity through an RNA Recognition Motif.
Sign Up to like & getrecommendations! Published in 2022 at "Plant physiology"
DOI: 10.1093/plphys/kiac081
Abstract: The activity of intracellular plant Nucleotide-Binding Leucine-Rich Repeat (NB-LRR) immune receptors is fine-tuned by interactions between the receptors and their partners. Identifying NB-LRR interacting proteins is therefore crucial to advance our understanding of how these… read more here.
Keywords: rich rna; recognition motif; rna recognition; glycine rich ... See more keywords
RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM
Sign Up to like & getrecommendations! Published in 2020 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-020-01021-5
Abstract: Background Amyotrophic lateral sclerosis (ALS) is an adult-onset, fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. While pathogenic mutations in the DNA/RNA-binding protein Matrin-3 (MATR3) are linked to ALS and… read more here.
Keywords: matr3; hnrnpm; rna recognition; matrin ... See more keywords
Structure and RNA recognition of ribosome assembly factor Utp30.
Sign Up to like & getrecommendations! Published in 2017 at "RNA"
DOI: 10.1261/rna.062695.117
Abstract: The 90S preribosomes are gigantic early assembly intermediates of small ribosomal subunits. Cryo-EM structures of 90S were recently determined, but many of its components have not been accurately modeled. Here we determine the crystal structure… read more here.
Keywords: structure rna; rna; structure; rna recognition ... See more keywords