Deletion of the RNA regulator HuR in tumor‐associated microglia and macrophages stimulates anti‐tumor immunity and attenuates glioma growth
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23696
Abstract: Glioblastoma is a malignant brain tumor that portends a poor prognosis. Its resilience, in part, is related to a remarkable capacity for manipulating the microenvironment to promote its growth and survival. Microglia/macrophages are prime targets,… read more here.
Keywords: tumor associated; hur; rna regulator; microglia macrophages ... See more keywords
A small RNA regulator of autophagy
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DOI: 10.1126/science.363.6431.1053-f
Abstract: Molecular Biology Autophagy serves an essential cellular-garbage disposal function. For example, the autophagy receptor p62 (or sequestosome-1) is needed for selective removal of intracellular pathogen material to the autophagosome for degradation. Notably, p62 must oligomerize… read more here.
Keywords: biology; small rna; rna regulator; regulator autophagy ... See more keywords