The RNA regulatory programs that govern lymphocyte development and function
Sign Up to like & getrecommendations! Published in 2021 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1683
Abstract: Lymphocytes require of constant and dynamic changes in their transcriptome for timely activation and production of effector molecules to combat external pathogens. Synthesis and translation of messenger (m)RNAs into these effector proteins is controlled both… read more here.
Keywords: regulatory programs; development; programs govern; function ... See more keywords
Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA–protein binding sites
Sign Up to like & getrecommendations! Published in 2017 at "Genome Biology"
DOI: 10.1186/s13059-017-1298-8
Abstract: Crosslinking immunoprecipitation sequencing (CLIP-seq) technologies have enabled researchers to characterize transcriptome-wide binding sites of RNA-binding protein (RBP) with high resolution. We apply a soft-clustering method, RBPgroup, to various CLIP-seq datasets to group together RBPs that… read more here.
Keywords: protein; high confidence; rna; binding sites ... See more keywords
Noncoding RNA:RNA Regulatory Networks in Cancer
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DOI: 10.3390/ijms19051310
Abstract: Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and has been implicated in many pathological conditions, especially… read more here.
Keywords: noncoding rna; networks cancer; rna regulatory; cancer ... See more keywords
RNA Regulatory Networks 2.0
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24109001
Abstract: The central role of RNA molecules in cell biology has been an expanding subject of study since the proposal of the "RNA world" hypothesis 60 years ago [...]. read more here.
Keywords: regulatory networks; biology; rna regulatory;