Organization of the Flavivirus RNA replicase complex
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1437
Abstract: Flaviviruses, such as dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses, are serious human pathogens that cause significant morbidity and mortality globally each year. Flaviviruses are single‐stranded, positive‐sense RNA viruses, and encode two… read more here.
Keywords: rna replicase; flavivirus rna; ns3 ns5; organization flavivirus ... See more keywords
nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.00355-21
Abstract: A key element of every virus with an RNA genome is the RNA replicase. Understanding the principles of RNA replicase formation and functioning is therefore crucial for understanding and responding to the emergence of new… read more here.
Keywords: rna replicase; formation; p123; virus ... See more keywords
In Silico Evaluation of Sesquiterpenes and Benzoxazinoids Phytotoxins against Mpro, RNA Replicase and Spike Protein of SARS-CoV-2 by Molecular Dynamics. Inspired by Nature
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DOI: 10.3390/toxins14090599
Abstract: In the work described here, a number of sesquiterpenes and benzoxazinoids from natural sources, along with their easily accessible derivatives, were evaluated against the main protease, RNA replicase and spike glycoprotein of SARS-CoV-2 by molecular… read more here.
Keywords: spike; spike protein; replicase spike; rna replicase ... See more keywords