Computational Identification of Small Interfering RNA Targets in SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2020 at "Virologica Sinica"
DOI: 10.1007/s12250-020-00221-6
Abstract: With the epidemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) worldwide and in the absence of any effective vaccine, there is an urgent need to find a specific anti- SARS-CoV-2 agent. In this study,… read more here.
Keywords: small interfering; identification small; interfering rna; rna targets ... See more keywords
The snoGloBe interaction predictor reveals a broad spectrum of C/D snoRNA RNA targets
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac475
Abstract: Box C/D small nucleolar RNAs (snoRNAs) are a conserved class of RNA known for their role in guiding ribosomal RNA 2’-O-ribose methylation. Recently, C/D snoRNAs were also implicated in regulating the expression of non-ribosomal genes… read more here.
Keywords: snoglobe; rna; interaction predictor; rna targets ... See more keywords
Characterization of METTL16 as a cytoplasmic RNA binding protein
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0227647
Abstract: mRNA modification by N6-methyladenosine (m6A) is involved in many post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the recently identified mRNA methylation complex containing METTL3, METTL14, and WTAP has been the… read more here.
Keywords: rna; rna binding; mettl16 cytoplasmic; mettl16 ... See more keywords
Comprehensive Bioinformatics Analysis to Reveal Key RNA Targets and Hub Competitive Endogenous RNA Network of Keratoconus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.896780
Abstract: Keratoconus (KC) is the most common corneal ectatic disease, with its pathological mechanisms unclear. We mainly performed bioinformatics approaches to reveal core RNA targets and hub competitive endogenous RNA (ceRNA) network and explored the potential… read more here.
Keywords: network; targets hub; mir; hub competitive ... See more keywords
The Evolution of Imprinted microRNAs and Their RNA Targets
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DOI: 10.3390/genes11091038
Abstract: Mammalian genomes contain many imprinted microRNAs. When an imprinted miRNA targets an unimprinted mRNA their interaction may have different fitness consequences for the loci encoding the miRNA and mRNA. In one possible outcome, the mRNA… read more here.
Keywords: imprinted micrornas; micrornas rna; rna targets; sequence ... See more keywords