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Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab364
Abstract: Abstract Motivation Trajectory inference (TI) for single cell RNA sequencing (scRNAseq) data is a powerful approach to interpret dynamic cellular processes such as cell cycle and development. Still, however, accurate inference of trajectory is challenging.…
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Keywords:
rna velocity;
trajectory;
based rna;
trajectory inference ... See more keywords
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Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010492
Abstract: We perform a thorough analysis of RNA velocity methods, with a view towards understanding the suitability of the various assumptions underlying popular implementations. In addition to providing a self-contained exposition of the underlying mathematics, we…
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Keywords:
rna velocity;
biology;
velocity unraveled;
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227873
Abstract: In recent years, single-cell RNA sequencing technology (scRNA-seq) has developed rapidly and has been widely used in biological and medical research, such as in expression heterogeneity and transcriptome dynamics of single cells. The investigation of…
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Keywords:
cell;
velocity;
prediction;
model ... See more keywords