Innate immune responses in RNA viral infection
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers of Medicine"
DOI: 10.1007/s11684-020-0776-7
Abstract: RNA viruses cause a multitude of human diseases, including several pandemic events in the past century. Upon viral invasion, the innate immune system responds rapidly and plays a key role in activating the adaptive immune… read more here.
Keywords: innate; innate immune; viral infection; rna viral ... See more keywords
Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.06.021
Abstract: Genome delivery to the proper cellular compartment for transcription and replication is a primary goal of viruses. However, methods for analyzing viral genome localization and differentiating genomes with high identity are lacking, making it difficult… read more here.
Keywords: replication infection; infection dynamics; genome labeling; rna viral ... See more keywords
Putative RNA viral sequences detected in an Ixodes scapularis-derived cell line.
Sign Up to like & getrecommendations! Published in 2017 at "Ticks and tick-borne diseases"
DOI: 10.1016/j.ttbdis.2016.10.005
Abstract: Ticks harbour various microorganisms, some of which act as pathogens of humans and animals. The recent advancement of genome sequencing technologies revealed that a wide range of previously unrecognised microorganisms exist in ticks. Continuous cell… read more here.
Keywords: sequences detected; putative rna; rna viral; viral sequences ... See more keywords
Novel RNA Viral Vectors for Chemically Regulated Gene Expression in Embryonic Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00214
Abstract: RNA viral vectors that replicate without DNA intermediates are attractive platforms for manipulation of cells for biomedical and veterinary applications because they have minimal risk of chromosomal integration. Vesicular stomatitis virus (VSV) vectors are among… read more here.
Keywords: viral vectors; gene expression; rna viral; embryonic stem ... See more keywords
VirBot: an RNA viral contig detector for metagenomic data
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad093
Abstract: Abstract Summary Without relying on cultivation, metagenomic sequencing greatly accelerated the novel RNA virus detection. However, it is not trivial to accurately identify RNA viral contigs from a mixture of species. The low content of… read more here.
Keywords: rna viral; rna; rna virus; detector ... See more keywords
A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections.
Sign Up to like & getrecommendations! Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.25390.1
Abstract: Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) from nuclear… read more here.
Keywords: binding sites; rbp binding; rna viral; dna ... See more keywords
VGEA: an RNA viral assembly toolkit
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.12129
Abstract: Next generation sequencing (NGS)-based studies have vastly increased our understanding of viral diversity. Viral sequence data obtained from NGS experiments are a rich source of information, these data can be used to study their epidemiology,… read more here.
Keywords: quality; sequencing reads; reference; vgea ... See more keywords