The impact of viremia on organ failure, biomarkers and mortality in a Swedish cohort of critically ill COVID-19 patients
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DOI: 10.1038/s41598-021-86500-y
Abstract: The spread of virus via the blood stream has been suggested to contribute to extra-pulmonary organ failure in Coronavirus disease 2019 (COVID-19). We assessed SARS-CoV-2 RNAemia (RNAemia) and the association between RNAemia and inflammation, organ… read more here.
Keywords: covid patients; rnaemia; organ failure; critically ill ... See more keywords
The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia
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DOI: 10.1128/mbio.01577-22
Abstract: We showed that persistent SARS-CoV-2 RNAemia is an independent predictor of severe COVID-19. We observed that SARS-CoV-2-targeted antibody maturation, specifically Fc-effector functions rather than neutralization, was strongly linked with the ability to rapidly clear viremia.… read more here.
Keywords: persistent sars; development; associated clearance; rnaemia ... See more keywords
Temporal Kinetics of RNAemia and Associated Systemic Cytokines in Hospitalized COVID-19 Patients
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DOI: 10.1128/msphere.00311-21
Abstract: Severe COVID-19 can be considered a systemic disease as many extrarespiratory complications occur. However, the systemic pathogenesis is poorly understood. ABSTRACT COVID-19 is associated with a wide range of extrarespiratory complications, of which the pathogenesis… read more here.
Keywords: rnaemia; rnaemia associated; patients develop; disease ... See more keywords