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   Articles with "rnai machinery" as a keyword



Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.

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recommendations! Published in 2019 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2019.03.003

Abstract: Myotonic dystrophy type 1 is an autosomal-dominant inherited disorder caused by the expansion of CTG repeats in the 3' untranslated region of the DMPK gene. The RNAs bearing these expanded repeats have a range of… read more here.

Keywords: repeats trigger; trigger disease; expanded cug; machinery ... See more keywords

The subcellular topology of the RNAi machinery is multifaceted and reveals adherens junctions as an epithelial hub

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-09795-1

Abstract: The RNA interference (RNAi) machinery is a key cellular mechanism catalyzing biogenesis and function of miRNAs to post-transcriptionally regulate mRNA expression. The RNAi machinery includes a set of protein complexes with subcellular localization traditionally presented… read more here.

Keywords: machinery multifaceted; adherens junctions; rnai machinery; topology ... See more keywords
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How RNAi machinery enters the world of telomerase

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recommendations! Published in 2019 at "Cell Cycle"

DOI: 10.1080/15384101.2019.1609834

Abstract: ABSTRACT Human telomerase holoenzyme consists of the catalytic component TERT and the template RNA TERC. However, a network of accessory proteins plays key roles in its assembly, localization and stability. Defects in genes involved in… read more here.

Keywords: telomerase; rnai machinery; machinery enters; world telomerase ... See more keywords

RNAi machinery regulates nutrient metabolism and fluconazole resistance in the pathogenic fungus Cryptococcus deneoformans.

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recommendations! Published in 2022 at "Medical mycology"

DOI: 10.1093/mmy/myac095

Abstract: The RNAi machinery has been extensively studied in plant and animal cells for their crucial roles in regulation of genome function. However, the potential roles of RNAi in controlling fungal growth and development have been… read more here.

Keywords: cryptococcus deneoformans; fluconazole resistance; resistance; rnai machinery ... See more keywords

Methylation of mycovirus DNA is mediated by the RNAi machinery in vegetative hyphae of Fusarium graminearum

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recommendations! Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf478

Abstract: Abstract DNA cytosine methylation is an important epigenetic mechanism for transposon silencing and gene regulation in fungi, particularly during sexual reproduction. However, its occurrence in vegetative hyphae and role in defense against mycoviruses is unclear.… read more here.

Keywords: methylation; rnai machinery; hyphae fusarium; vegetative hyphae ... See more keywords