siRNA Specificity: RNAi Mechanisms and Strategies to Reduce Off-Target Effects
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DOI: 10.3389/fpls.2020.526455
Abstract: Short interfering RNAs (siRNAs) are processed from long double-stranded RNA (dsRNA), and a guide strand is selected and incorporated into the RNA-induced silencing complex (RISC). Within RISC, a member of the Argonaute protein family directly… read more here.
Keywords: target effects; sirna specificity; specificity rnai; rnai mechanisms ... See more keywords