RNAi-mediated knockdown of MCM7 gene on CML cells and its therapeutic potential for leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Medical Oncology"
DOI: 10.1007/s12032-016-0878-x
Abstract: MCM7 is one of the subunits of MCM2-7 complex, which is essential to DNA replication licensing and the control of cell cycle progression. It has been demonstrated that MCM7 participates in mRNA transcription and DNA… read more here.
Keywords: mcm7 gene; mediated knockdown; rnai mediated; gene ... See more keywords
RNAi-mediated down-regulation of ITPK-2 enhanced inorganic phosphorus and minerals in the transgenic rice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biosciences"
DOI: 10.1007/s12038-021-00154-6
Abstract: Phytic acid or Myo-inositol hexakisphosphate is an essential compound for the rice plants. It remains in the form of phytate, a mixed salt of different mineral cations, in the seeds. The phytate breaks down during… read more here.
Keywords: phytic acid; rice; rnai mediated; itpk ... See more keywords
RNAi-mediated disruption of neuropeptide genes, nlp-3 and nlp-12, cause multiple behavioral defects in Meloidogyne incognita.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.143
Abstract: Owing to the current deficiencies in chemical control options and unavailability of novel management strategies, root-knot nematode (M. incognita) infections remain widespread with significant socio-economic impacts. Helminth nervous systems are peptide-rich and appear to be putative… read more here.
Keywords: disruption neuropeptide; nlp nlp; genes nlp; mediated disruption ... See more keywords
RNAi-mediated antiviral immunity in insects and their possible application.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2018.10.004
Abstract: Antiviral RNA interference (RNAi) in insects is known for some time. Previously, data from the model organism Drosophila was lightly transferred to other insects. However, since more research is performed on other insects, both similarities… read more here.
Keywords: insects; antiviral immunity; mediated antiviral; rnai ... See more keywords
RNAi-Mediated Silencing of ITPK Gene Reduces Phytic Acid Content, Alters Transcripts of Phytic Acid Biosynthetic Genes, and Modulates Mineral Distribution in Rice Seeds
Sign Up to like & getrecommendations! Published in 2020 at "Rice Science"
DOI: 10.1016/j.rsci.2020.05.007
Abstract: Abstract Phytic acid is the principal storage form of phosphorus in plant seeds and an essential signalling molecule in several regulatory processes of plant development. However, it is known as an anti-nutrient compound owing to… read more here.
Keywords: phytic acid; rice; acid content; rnai mediated ... See more keywords
Expression of Concern: RNAi Mediated Tiam1 Gene Knockdown Inhibits Invasion of Retinoblastoma
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0252495
Abstract: The corresponding authors indicated that errors were made during the compilations of Figs 5 and 8 resulting in accidental duplications of the Fig 5B 0hr Y79 Untreated panel and the Fig 8B 0hr Weri-Rb1 Full… read more here.
Keywords: concern rnai; fig 0hr; expression concern; rnai mediated ... See more keywords
RNAi-mediated gene silencing in Rhynchophorus ferrugineus (Oliver) (Coleoptera: Curculionidae)
Sign Up to like & getrecommendations! Published in 2017 at "Open Life Sciences"
DOI: 10.1515/biol-2017-0025
Abstract: Abstract RNA interference (RNAi) is a powerful strategy for gene function analysis, and it is also widely studied in view of a promising use in pest control. The red palm weevil, Rhynchophorus ferrugineus (Oliver) (Coleoptera:… read more here.
Keywords: rhynchophorus ferrugineus; oliver coleoptera; ferrugineus oliver; rnai mediated ... See more keywords
RNAi-mediated gene silencing of Phlebotomus papatasi defensins favors Leishmania major infection
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1182141
Abstract: Introduction: Production of different antimicrobial peptides (AMPs) is one of the insect’s prominent defense strategies, regulated mainly by Toll and immune deficiency (IMD) humoral pathways. Here we focused mainly on two AMPs of Phlebotomus papatasi,… read more here.
Keywords: sand fly; rnai mediated; phlebotomus papatasi; leishmania major ... See more keywords
RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene
Sign Up to like & getrecommendations! Published in 2017 at "Genes"
DOI: 10.3390/genes8110303
Abstract: The microaerophilic protozoan Giardia lamblia is the agent causing giardiasis, an intestinal parasitosis of worldwide distribution. Different pharmacotherapies have been employed against giardiasis; however, side effects in the host and reports of drug resistant strains… read more here.
Keywords: drug targets; drug; giardia lamblia; rnai mediated ... See more keywords
RNAi-Mediated Knockdown of Transcription Factor E93 in Nymphs of the Desert Locust (Schistocerca gregaria) Inhibits Adult Morphogenesis and Results in Supernumerary Juvenile Stages
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21207518
Abstract: Postembryonic development of insects is coordinated by juvenile hormone (JH) together with ecdysteroids. Whereas the JH early response gene krüppel-homolog 1 (Kr-h1) plays a crucial role in the maintenance of juvenile characteristics during consecutive larval… read more here.
Keywords: desert locust; adult morphogenesis; locust schistocerca; mediated knockdown ... See more keywords
RNAi Mediated Hypoxia Stress Tolerance in Plants
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21249394
Abstract: Small RNAs regulate various biological process involved in genome stability, development, and adaptive responses to biotic or abiotic stresses. Small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs). MicroRNAs (miRNAs) are regulators of gene… read more here.
Keywords: hypoxia stress; stress; small rnas; mediated hypoxia ... See more keywords