Small non-coding RNAs-based bone regulation and targeting therapeutic strategies
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.11.018
Abstract: Abstract Small non-coding RNAs, which are 20–25 nucleotide ribonucleic acids, have emerged as an important transformation in the biological evolution over almost three decades. microRNAs (miRNAs) and short interfering RNAs (siRNAs) are two significant categories… read more here.
Keywords: endocrinology; coding rnas; rnas based; small non ... See more keywords
Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "EMBO reports"
DOI: 10.15252/embr.201745336
Abstract: Trinucleotide repeat (TNR) expansions in the genome cause a number of degenerative diseases. A prominent TNR expansion involves the triplet CAG in the huntingtin (HTT) gene responsible for Huntington's disease (HD). Pathology is caused by… read more here.
Keywords: toxic cancer; rnas based; small interfering; cancer cells ... See more keywords