Impact of noncoding RNAs on cancer directed immune therapies: Now then and forever
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34060
Abstract: Accumulating evidence demonstrates that the host genome's epigenetic modifications are essential for living organisms to adapt to extreme conditions. DNA methylation, covalent modifications of histone and interassociation of noncoding RNAs facilitate the cellular manifestation of… read more here.
Keywords: rnas cancer; tumor development; noncoding rnas; cancer directed ... See more keywords
Chimeric RNAs in cancer and normal physiology
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1427
Abstract: Traditionally, chimeric RNAs were considered to be exclusive to cancer cells. When occasionally observed in normal samples, they were usually considered to be transcriptional ‘noises,’ or artifacts due to template switching during the reverse transcription… read more here.
Keywords: chimeric rnas; physiology; rnas cancer; normal physiology ... See more keywords
Long noncoding RNAs in cancer cells.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.01.053
Abstract: Long noncoding RNA (lncRNA) has recently been investigated as key modulators that regulate many biological processes in human cancers via diverse mechanisms. LncRNAs can interact with macromolecules such as DNA, RNA, or protein to exert… read more here.
Keywords: rnas cancer; long noncoding; noncoding rnas; cancer cells ... See more keywords
Enhancer RNAs in cancer: regulation, mechanisms and therapeutic potential
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DOI: 10.1080/15476286.2020.1712895
Abstract: ABSTRACT Enhancers are distal genomic elements critical for gene regulation and cell identify control during development and diseases. Many human cancers were found to associate with enhancer malfunction, due to genetic and epigenetic alterations, which… read more here.
Keywords: gene regulation; rnas cancer; cancer; enhancer rnas ... See more keywords
Abstract SY32-04: About Chomsky, patterns, and noncoding RNAs cancer therapeutics
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-sy32-04
Abstract: Resistance to therapy is an important issue in the treatment of cancer, responsible for many cancer-related deaths. Despites decades of research into overcoming this resistance, only modest advances have been made and the resistance mechanisms… read more here.
Keywords: rnas cancer; patterns noncoding; noncoding rnas; cancer ... See more keywords
PIWI-interacting RNAs in cancer: Biogenesis, function, and clinical significance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.965684
Abstract: PIWI-interacting RNAs (piRNAs) are a less-studied class of small non-coding RNAs approximately 24–31 nucleotides in length. They express in germline and somatic cells and form complexes with PIWI proteins to exert regulatory effects. New studies… read more here.
Keywords: piwi interacting; biogenesis function; rnas cancer; interacting rnas ... See more keywords
Non-Coding RNAs in Cancer Diagnosis and Therapy: Focus on Lung Cancer
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DOI: 10.3390/cancers13061372
Abstract: Simple Summary Researchers have spent nearly two decades unraveling the roles of non-coding RNAs in cancer biology. In recent years, deep transcriptomic profiling of tissue and circulating non-coding RNAs in cancer patients have elucidated non-coding… read more here.
Keywords: rnas cancer; coding rnas; non coding; biology ... See more keywords
The Nefarious Nexus of Noncoding RNAs in Cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19072072
Abstract: The past decade has witnessed enormous progress, and has seen the noncoding RNAs (ncRNAs) turn from the so-called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts. Many… read more here.
Keywords: rnas cancer; nexus noncoding; nefarious nexus; noncoding rnas ... See more keywords