Decay of Piwi-Interacting RNAs in Human Cells Is Primarily Mediated by 5' to 3' Exoribonucleases.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00007
Abstract: Piwi-interacting RNAs (piRNAs) are a group of small noncoding RNA molecules that regulate the activity of transposons and control gene expression. The cellular concentration of RNAs is generally maintained by their rates of biogenesis and… read more here.
Keywords: piwi interacting; rnas human; interacting rnas; degradation ... See more keywords
tRNA-derived small RNAs in human cancers: roles, mechanisms, and clinical application
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DOI: 10.1186/s12943-024-01992-2
Abstract: Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are a new type of non-coding RNAs (ncRNAs) produced by the specific cleavage of precursor or mature tRNAs. tsRNAs are involved in various basic biological processes such as epigenetic,… read more here.
Keywords: derived small; small rnas; tumor; rnas human ... See more keywords
Long Noncoding RNAs in Human Cancer and Apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201023666220624094950
Abstract: Genome annotations have uncovered the production of at least one transcript from nearly all loci in the genome at some given time throughout the development. Surprisingly a big chunk of these transcripts does not code… read more here.
Keywords: apoptosis; long noncoding; noncoding rnas; rnas human ... See more keywords
Editorial: Non-Coding RNAs and Human Diseases
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DOI: 10.3389/fgene.2020.00523
Abstract: Non-coding RNA (ncRNA) are functional RNA molecules that are not translatable into proteins (Djebali et al., 2012; Lonsdale et al., 2013; Forrest et al., 2014). Initially, ncRNAs referred to tRNAs and rRNAs (Brown et al.,… read more here.
Keywords: coding rnas; rna; non coding; editorial non ... See more keywords
Small Non-Coding RNAs in the Human Placenta: Regulatory Roles and Clinical Utility
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DOI: 10.3389/fgene.2022.868598
Abstract: The placenta is a vital organ formed during pregnancy, and being the interface between the mother and fetus, it is paramount that placental functioning is strictly controlled. Gene expression in the placenta is finely tuned—with… read more here.
Keywords: human placenta; coding rnas; placenta; rnas human ... See more keywords
Editorial for the “Non-Coding RNAs in Human Health and Disease” Special Issue
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DOI: 10.3390/genes16020211
Abstract: Numerous non-coding RNA (ncRNA) species, including miRNAs, siRNAs, piRNAs, circRNAs, and lncRNAs, have displayed a substantial correlation with human diseases, and may serve as prospective targets for gene therapy and diagnostic biomarkers [...]. read more here.
Keywords: non coding; health disease; coding rnas; editorial non ... See more keywords
The Role of Long Noncoding RNAs in Human Papillomavirus-associated Pathogenesis
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DOI: 10.3390/pathogens9040289
Abstract: Infections with high-risk human papillomaviruses cause ~5% of all human cancers. E6 and E7 are the only viral genes that are consistently expressed in cancers, and they are necessary for tumor initiation, progression, and maintenance.… read more here.
Keywords: role long; long noncoding; noncoding rnas; human papillomavirus ... See more keywords