Circular RNAs: Novel Biomarkers in Spermatogenesis Defects and Male Infertility
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Sciences"
DOI: 10.1007/s43032-022-00885-3
Abstract: Circular RNAs (circRNAs) are a new class of endogenous non-coding RNAs involved in several cellular and biological processes, including gene expression regulation, microRNA function, transcription regulation, and translation modification. Therefore, these non-coding RNAs have important… read more here.
Keywords: defects male; spermatogenesis; circular rnas; infertility ... See more keywords
Circular RNAs as novel regulators of β-cell functions in normal and disease conditions
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2018.01.010
Abstract: Objective There is strong evidence for an involvement of different classes of non-coding RNAs, including microRNAs and long non-coding RNAs, in the regulation of β-cell activities and in diabetes development. Circular RNAs were recently discovered… read more here.
Keywords: circular rnas; coding rnas; non coding; rnas novel ... See more keywords
Circular RNAs: novel diagnostic and therapeutic targets for ischemic stroke
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2020.1826313
Abstract: ABSTRACT Introduction Ischemic stroke is a life-threatening condition worldwide, including China. Nowadays, intravenous thrombolysis and mechanical thrombectomy are chiefly applied as clinical therapeutics; however, strict time windows and underlying risks limit their benefits for patients.… read more here.
Keywords: ischemic stroke; circular rnas; novel diagnostic; therapeutic targets ... See more keywords
Circular RNAs: A novel type of biomarker and genetic tools in cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18350
Abstract: Circular RNAs (circRNAs) are a novel type of universal and diverse endogenous noncoding RNAs (ncRNAs) and they form a covalently closed continuous loop without 5′ or 3′ tails unlike linear RNAs. Most circRNAs are presented… read more here.
Keywords: type biomarker; circular rnas; novel type; rnas novel ... See more keywords
Transfer RNA-Derived Small RNAs: Novel Regulators and Biomarkers of Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.843598
Abstract: Transfer RNA-derived small RNAs (tsRNAs) are conventional non-coding RNAs (ncRNAs) with a length between18 and 40 nucleotides (nt) playing a crucial role in treating various human diseases including tumours. Nowadays, with the use of high-throughput… read more here.
Keywords: transfer rna; rna derived; rnas novel; derived small ... See more keywords
Long Noncoding RNAs: Novel Important Players in Adipocyte Lipid Metabolism and Derivative Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.691824
Abstract: Obesity, a global public health issue, is characterized by excessive adiposity and is strongly related to some chronic diseases including cardiovascular diseases and diabetes. Extra energy intake-induced adipogenesis involves various transcription factors and long noncoding… read more here.
Keywords: long noncoding; novel important; rnas novel; adipose tissue ... See more keywords
Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21051838
Abstract: Mitochondria are organelles responsible for several functions involved in cellular balance, including energy generation and apoptosis. For decades now, it has been well-known that mitochondria have their own genetic material (mitochondrial DNA), which is different… read more here.
Keywords: dna; coding rnas; non coding; epigenetics non ... See more keywords
Circular RNAs as Novel Regulators of β-Cell Functions under Physiological and Pathological Conditions
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041503
Abstract: Circular RNAs (circRNAs) constitute a large class of non-coding RNAs characterized by a covalently closed circular structure. They originate during mRNA maturation through a modification of the splicing process and, according to the included sequences,… read more here.
Keywords: circular rnas; pathological conditions; rnas novel; regulators cell ... See more keywords
Exosomal RNAs: Novel Potential Biomarkers for Diseases—A Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052461
Abstract: Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes. Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs, miRNAs, lncRNAs, and circRNAs. Exosomal RNAs have cell specificity and reflect the conditions of… read more here.
Keywords: potential biomarkers; exosomal rnas; rnas novel; diseases review ... See more keywords