Characterization of Impurities in Therapeutic RNAs at the Single Nucleotide Level.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04681
Abstract: The chemistry of guide RNA (gRNA) affects the performance of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 genome editing technique. However, the literature is very scarce about the study of gRNA degradation and in… read more here.
Keywords: characterization impurities; nucleotide level; chemistry; rnas single ... See more keywords
Identification and Functional Analysis of Transcriptome Profiles, Long Non-Coding RNAs, Single-Nucleotide Polymorphisms, and Alternative Splicing from the Oocyte to the Preimplantation Stage of Sheep by Single-Cell RNA Sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14061145
Abstract: Numerous dynamic and complicated processes characterize development from the oocyte to the embryo. However, given the importance of functional transcriptome profiles, long non-coding RNAs, single-nucleotide polymorphisms, and alternative splicing during embryonic development, the effect that… read more here.
Keywords: long non; coding rnas; rnas single; profiles long ... See more keywords