RNase III Nucleases and the Evolution of Antiviral Systems
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DOI: 10.1002/bies.201700173
Abstract: Every living entity requires the capacity to defend against viruses in some form. From bacteria to plants to arthropods, cells retain the capacity to capture genetic material, process it in a variety of ways, and… read more here.
Keywords: nucleases evolution; capacity; evolution antiviral; antiviral systems ... See more keywords
Structural basis for Dicer-like function of an engineered RNase III variant and insights into the reaction trajectory of two-Mg2+-ion catalysis
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DOI: 10.1080/15476286.2022.2099650
Abstract: ABSTRACT The RNase III family of dsRNA-specific endonucleases is exemplified by prokaryotic RNase III and eukaryotic Rnt1p, Drosha, and Dicer. Structures of Aquifex aeolicus RNase III (AaRNase III) and Saccharomyces cerevisiae Rnt1p (ScRnt1p) show that… read more here.
Keywords: two mg2; rnase; rnase iii; mg2 ion ... See more keywords
Domain function and predicted structure of three heterodimeric endonuclease subunits of RNA editing catalytic complexes in Trypanosoma brucei
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DOI: 10.1093/nar/gkac753
Abstract: Abstract Each of the three similar RNA Editing Catalytic Complexes (RECCs) that perform gRNA-directed uridine insertion and deletion during Trypanosoma brucei mitochondrial (mt) mRNA editing has a distinct endonuclease activity that requires two related RNase… read more here.
Keywords: rna editing; trypanosoma brucei; endonuclease; catalytic complexes ... See more keywords
The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx820
Abstract: Abstract RNase III enzymes cleave double stranded (ds)RNA. This is an essential step for regulating the processing of mRNA, rRNA, snoRNA and other small RNAs, including siRNA and miRNA. Arabidopsis thaliana encodes nine RNase III:… read more here.
Keywords: conserved cysteine; rnase; double stranded; stranded rna ... See more keywords
Distinct and redundant functions of three homologs of RNase III in the cyanobacterium Synechococcus sp. strain PCC 7002
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky041
Abstract: Abstract RNase III is a ribonuclease that recognizes and cleaves double-stranded RNA. Across bacteria, RNase III is involved in rRNA maturation, CRISPR RNA maturation, controlling gene expression, and turnover of messenger RNAs. Many organisms have… read more here.
Keywords: strain; rnase iii; pcc 7002; iii ... See more keywords
Regulatory Interplay between RNase III and Antisense RNAs in E. coli: the Case of AsflhD and FlhD, Component of the Master Regulator of Motility
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DOI: 10.1128/mbio.00981-22
Abstract: The role of antisense RNAs (asRNAs) in the regulation of gene expression remains largely unexplored in bacteria. Here, we confirm that asRNAs can be part of layered regulatory networks, since some are found opposite to… read more here.
Keywords: motility; rnase iii; antisense rnas; expression ... See more keywords
Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei.
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DOI: 10.1261/rna.071258.119
Abstract: Multiprotein editosomes catalyze gRNA-specified insertion and deletion of uridines to create functional mitochondrial mRNAs in Trypanosoma brucei. Three functionally distinct editosomes are distinguished by their single KREN1, KREN2, or KREN3 RNase III endonuclease and, respectively,… read more here.
Keywords: rnase; trypanosoma brucei; rnase iii; krepb7 krepb8 ... See more keywords
Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs
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DOI: 10.1371/journal.ppat.1010202
Abstract: The exogenous small interfering RNA (exo-siRNA) pathway is a key antiviral mechanism in the Aedes aegypti mosquito, a widely distributed vector of human-pathogenic arboviruses. This pathway is induced by virus-derived double-stranded RNAs (dsRNA) that are… read more here.
Keywords: small interfering; activity; rnase iii; dcr2 ... See more keywords
RNase III coding genes modulate the cross-kingdom biofilm of Streptococcus mutans and Candida albicans
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DOI: 10.3389/fmicb.2022.957879
Abstract: Streptococcus mutans constantly coexists with Candida albicans in plaque biofilms of early childhood caries (ECC). The progression of ECC can be influenced by the interactions between S. mutans and C. albicans through exopolysaccharides (EPS). Our… read more here.
Keywords: cross kingdom; kingdom biofilm; kingdom; rnase iii ... See more keywords