Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz572
Abstract: Abstract RNase P RNA (RPR), the catalytic subunit of the essential RNase P ribonucleoprotein, removes the 5′ leader from precursor tRNAs. The ancestral eukaryotic RPR is a Pol III transcript generated with mature termini. In… read more here.
Keywords: rnase rna; intron; rnase; rna ... See more keywords
Characterization of RNA-based and protein-only RNases P from bacteria encoding both enzyme types.
Sign Up to like & getrecommendations! Published in 2023 at "RNA"
DOI: 10.1261/rna.079459.122
Abstract: A small group of bacteria encode two types of RNase P, the classical ribonucleoprotein (RNP) RNase P as well as the protein-only RNase P HARP (Homolog of Aquifex RNase P). We characterized the dual RNase… read more here.
Keywords: indicus rnase; rna; rnase; characterization rna ... See more keywords
Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0192873
Abstract: The natural trans-acting ribozyme RNase P RNA (RPR) is composed of two domains in which the catalytic (C-) domain mediates cleavage of various substrates. The C-domain alone, after removal of the second specificity (S-) domain,… read more here.
Keywords: rnase rna; cleavage; specificity domain; rpr ... See more keywords