Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44798-9
Abstract: Subcellular RNAseq promises to dissect transcriptional dynamics but is not well characterized. Furthermore, FACS may introduce bias but has not been benchmarked genome-wide. Finally, D1 and D2 dopamine receptor-expressing medium spiny neurons (MSNs) of the… read more here.
Keywords: spiny neurons; biology; nucleus accumbens; medium spiny ... See more keywords
TSAFinder: exhaustive tumor-specific antigen detection with RNAseq
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac116
Abstract: MOTIVATION Tumor specific antigen (TSA) identification in human cancer predicts response to immunotherapy and provides targets for cancer vaccine and adoptive T-cell therapies with curative potential, and TSAs that are highly expressed at the RNA… read more here.
Keywords: tumor specific; rnaseq; specific antigen; tumor ... See more keywords
Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma.
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2020007081
Abstract: Emergence of drug resistance to all available therapies is the major challenge to improving survival in myeloma. Cereblon (CRBN) is the essential binding protein of the widely used immunomodulatory drugs (IMiDs) and novel CRBN E3… read more here.
Keywords: myeloma; lenalidomide; multiple cereblon; resistance ... See more keywords
DiCoExpress: a tool to process multifactorial RNAseq experiments from quality controls to co-expression analysis through differential analysis based on contrasts inside GLM models
Sign Up to like & getrecommendations! Published in 2020 at "Plant Methods"
DOI: 10.1186/s13007-020-00611-7
Abstract: Background RNAseq is nowadays the method of choice for transcriptome analysis. In the last decades, a high number of statistical methods, and associated bioinformatics tools, for RNAseq analysis were developed. More recently, statistical studies realised… read more here.
Keywords: rnaseq; quality controls; analysis; expression analysis ... See more keywords
Nanopore long-read RNAseq reveals transcriptional variations in citrus species
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1077797
Abstract: The number of studies on plant transcriptomes using ONT RNAseq technology is rapidly increasing in recent. It is a powerful method to decipher transcriptomic complexity, particularly alternative splicing (AS) event detection. Citrus plants are the… read more here.
Keywords: nanopore long; rnaseq; rnaseq reveals; read rnaseq ... See more keywords