Articles with "rnf12 rlim" as a keyword



Chromatin targeting of the RNF12/RLIM E3 ubiquitin ligase controls transcriptional responses

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Published in 2024 at "Life Science Alliance"

DOI: 10.26508/lsa.202302282

Abstract: The E3 ubiquitin ligase RNF12/RLIM is mutated in intellectual disability and controls developmental gene expression. We show that chromatin targeting of RNF12 is required for substrate ubiquitylation and transcriptional responses, providing insight into mechanisms by… read more here.

Keywords: transcriptional responses; chromatin targeting; rnf12 rlim; ubiquitin ligase ... See more keywords