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Published in 2024 at "Life Science Alliance"
DOI: 10.26508/lsa.202302282
Abstract: The E3 ubiquitin ligase RNF12/RLIM is mutated in intellectual disability and controls developmental gene expression. We show that chromatin targeting of RNF12 is required for substrate ubiquitylation and transcriptional responses, providing insight into mechanisms by…
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Keywords:
transcriptional responses;
chromatin targeting;
rnf12 rlim;
ubiquitin ligase ... See more keywords