RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of Vaccinia Related Kinase3.
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DOI: 10.1242/jcs.247304
Abstract: Vaccinia-related kinase 3 (VRK3) has been reported to be a negative regulator of ERK that protects cells from persistent ERK activation and inhibits ERK dependent apoptosis. Here we report that the E3 ligase, RNF144a, promotes… read more here.
Keywords: vrk3; rnf144a; erk dependent; vaccinia related ... See more keywords