Rnf144b alleviates the inflammatory responses and cardiac dysfunction in sepsis.
Sign Up to like & getrecommendations! Published in 2023 at "ESC heart failure"
DOI: 10.1002/ehf2.14383
Abstract: AIMS Sepsis is an inflammatory disease with high mortality and morbidity. Inflammation plays an essential role in sepsis, and suppressing inflammation has been shown to ameliorate sepsis. Rnf144b is an ubiquitin E3 ligation with anti-inflammation… read more here.
Keywords: sepsis; rnf144b; inflammatory responses; responses cardiac ... See more keywords
RNF144B inhibits LPS‐induced inflammatory responses via binding TBK1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2a0819-055r
Abstract: Innate immune responses need to be precisely controlled to avoid prolonged inflammation and prevent unwanted damage to the host. Here, we report that RNF144B responded dynamically to LPS stimulation and negatively regulated LPS‐induced inflammation. We… read more here.
Keywords: rnf144b inhibits; inhibits lps; tbk1; induced inflammatory ... See more keywords