RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination
Sign Up to like & getrecommendations! Published in 2023 at "Cell Cycle"
DOI: 10.1080/15384101.2023.2205201
Abstract: ABSTRACT Osteosarcoma (OS) is still the most common malignant bone tumor whose etiology remains largely unclear. Here, we aimed to investigate the role of a novel E3 ubiquitin ligase RING finger gene 180 (RNF180) in… read more here.
Keywords: cbx4; ring finger; finger gene; rnf180 ... See more keywords
RNF180 Inhibits Proliferation and Promotes Apoptosis of Colorectal Cancer Through Ubiquitination of WISP1
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DOI: 10.3389/fcell.2020.623455
Abstract: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths globally and is biologically and clinically heterogeneous. Due to lack of gene expression signatures for risk and prognosis stratification of CRC, identifying novel molecular… read more here.
Keywords: tumor growth; colorectal cancer; rnf180; crc ... See more keywords
RNF180 weakened the lipid droplet formation and subsequent chemoresistance by destabilizing ACC1 and ACLY in esophageal cancer
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1525431
Abstract: Objective RNF180 (Ring finger protein 180) is an E3 ubiquitin-protein ligase that promotes polyubiquitination and proteasomal degradation. The study aimed to clarify the clinicopathological significances, signal pathways and molecular mechanisms of RNF180 expression in esophageal… read more here.
Keywords: expression; rnf180; acc1 acly; esophageal cancer ... See more keywords