Articles with "rnf20" as a keyword



RNF20 deletion causes inflammation in model of sepsis through the NLRP3 Activation.

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Published in 2023 at "Immunopharmacology and immunotoxicology"

DOI: 10.1080/08923973.2023.2170241

Abstract: Sepsis is an extremely complex, threatening and difficult-to-treat disease, which can occur at any age and under any underlying disease. RNF20 regulate NF-kappaB (NF-κB) signaling pathway and the transcription of inflammatory factors of target genes.… read more here.

Keywords: sepsis; rnf20; model sepsis; inflammation reactions ... See more keywords

RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes

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Published in 2019 at "Diabetes"

DOI: 10.2337/db19-0508

Abstract: Adipose tissue is the key organ coordinating whole-body energy homeostasis. Although it has been reported that ring finger protein 20 (RNF20) regulates lipid metabolism in the liver and kidney, the roles of RNF20 in adipose… read more here.

Keywords: ppar; degradation; rnf20; transcriptional activity ... See more keywords

The Islet-1 Interaction Partner Rnf20 Regulates Glucose Homeostasis and Pancreatic β-Cell Identity

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Published in 2025 at "Diabetes"

DOI: 10.2337/db25-0167

Abstract: Diabetes is characterized by a loss of functional β-cell mass; therefore, identifying factors involved in establishing and preserving β-cells is critical to combat rising diabetes incidence. While transcription factors are crucial β-cell regulators, knowledge of… read more here.

Keywords: isl1; rnf20; glucose homeostasis; cell ... See more keywords