Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer
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DOI: 10.1038/s41420-021-00449-5
Abstract: Colorectal cancer (CRC) is the third most common cancer worldwide. Several studies have suggested that taraxasterol acetate (TA) can inhibit the growth of tumor cells. However, to date, it remains unclear how TA inhibits cell… read more here.
Keywords: degradation; rnf31; colorectal cancer; taraxasterol acetate ... See more keywords
Identification and molecular analysis of RNF31 Q622H germline polymorphism
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DOI: 10.3892/ol.2022.13514
Abstract: The linear ubiquitin chain assembly complex (LUBAC), which is composed of RING finger protein 31 (RNF31), RANBP2-type and C3HC4-type zinc finger containing 1 and SHANK-associated RH domain interactor subunits, is the only ubiquitin ligase to… read more here.
Keywords: rnf31; q584h q622l; rnf31 q622h; q622h ... See more keywords