Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA
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DOI: 10.1093/nar/gkab513
Abstract: Abstract The rnlAB toxin-antitoxin operon from Escherichia coli functions as an anti-phage defense system. RnlA was identified as a member of the HEPN (Higher Eukaryotes and Prokaryotes Nucleotide-binding domain) superfamily of ribonucleases. The activity of… read more here.
Keywords: hepn; required activity; rnla; canonical hepn ... See more keywords