Articles with "rnls8 mice" as a keyword



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Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice

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Published in 2019 at "Neurobiology of Disease"

DOI: 10.1016/j.nbd.2018.11.013

Abstract: Therapeutic strategies are needed for the treatment of amyotrophic lateral sclerosis (ALS). One potential target is matrix metalloproteinase-9 (MMP-9), which is expressed only by fast motor neurons (MNs) that are selectively vulnerable to various ALS-relevant… read more here.

Keywords: metalloproteinase mmp; rnls8 mice; motor; matrix metalloproteinase ... See more keywords