mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription
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DOI: 10.1016/j.celrep.2018.04.004
Abstract: Summary mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II transcription independent of mRNA capping and… read more here.
Keywords: transcription; rnmt ram; ram; rna pol ... See more keywords
c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production
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DOI: 10.1042/bcj20160930
Abstract: The mRNA cap is a structure added to RNA pol II transcripts in eukaryotes, which recruits factors involved in RNA processing, nuclear export and translation initiation. RNA guanine-7 methyltransferase (RNMT)–RNA-activating miniprotein (RAM), the mRNA cap… read more here.
Keywords: rna; mrna cap; rnmt ram; cap ... See more keywords