Rhinacanthus nasutus and okara polysaccharides attenuate colitis via inhibiting inflammation and modulating the gut microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7582
Abstract: Plant polysaccharides have prebiotic properties for gut microbiota and immune modulation. This study aimed to investigate the prevention abilities of edible Rhinacanthus nasutus polysaccharide (RNP) and okara polysaccharide (OP) in Sprague–Dawley rats with acetic acid‐induced… read more here.
Keywords: rhinacanthus nasutus; colitis; rnp; gut microbiota ... See more keywords
The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10554-w
Abstract: Prion-like domains (PLDs), defined by their low sequence complexity and intrinsic disorder, are present in hundreds of human proteins. Although gain-of-function mutations in the PLDs of neuronal RNA-binding proteins have been linked to neurodegenerative disease… read more here.
Keywords: imp; rnp granules; prion like; rnp ... See more keywords
Ranpirnase Reduces HIV-1 Infection and Associated Inflammatory Changes in a Human Colorectal Explant Model.
Sign Up to like & getrecommendations! Published in 2018 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2017.0308
Abstract: Ranpirnase (RNP) is a low molecular weight type III endoribonuclease, which demonstrates broad antiviral and antitumor properties. We sought to characterize the antiviral activity of RNP against HIV-1 and to determine whether RNP modulates local… read more here.
Keywords: hiv infection; inflammatory changes; infection; explant model ... See more keywords
The dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac487
Abstract: Abstract Mature microRNAs are bound by a member of the Argonaute (Ago1-4) protein family, forming the core of the RNA-induced silencing complex (RISC). Association of RISC with target mRNAs results in ribonucleoprotein (RNP) assembly involved… read more here.
Keywords: governs rnp; rnp; argonaute; staufen2 governs ... See more keywords
The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01405-22
Abstract: Bunyaviruses are emerging RNA viruses that cause significant disease and economic burden and for which vaccines or therapies approved for humans are not available. The bunyavirus genome is wrapped up by the nucleoprotein (NP) and… read more here.
Keywords: rnp; microscopy; rna; model ... See more keywords
Archaeal fibrillarin-Nop5 heterodimer 2'-O-methylates RNA independently of the C/D guide RNP particle.
Sign Up to like & getrecommendations! Published in 2017 at "RNA"
DOI: 10.1261/rna.059832.116
Abstract: Archaeal fibrillarin (aFib) is a well-characterized S-adenosyl methionine (SAM)-dependent RNA 2'-O-methyltransferase that is known to act in a large C/D ribonucleoprotein (RNP) complex together with Nop5 and L7Ae proteins and a box C/D guide RNA.… read more here.
Keywords: nop5 heterodimer; archaeal fibrillarin; fibrillarin nop5; rnp ... See more keywords
The Dynamic Network of RNP RNase P Subunits
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910307
Abstract: Ribonuclease P (RNase P) is an important ribonucleoprotein (RNP), responsible for the maturation of the 5′ end of precursor tRNAs (pre-tRNAs). In all organisms, the cleavage activity of a single phosphodiester bond adjacent to the… read more here.
Keywords: network rnp; rnase; rnp rnase; dynamic network ... See more keywords
First Report on Genome Editing via Ribonucleoprotein (RNP) in Castanea sativa Mill.
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105762
Abstract: Castanea sativa is an important tree nut species worldwide, highly appreciated for its multifunctional role, in particular for timber and nut production. Nowadays, new strategies are needed to achieve plant resilience to diseases, climate change,… read more here.
Keywords: crispr cas9; rnp; report genome; first report ... See more keywords
不同生境条件下滨海芦苇湿地C、N、P化学计量特征
Sign Up to like & getrecommendations! Published in 2018 at "Acta Ecologica Sinica"
DOI: 10.5846/stxb201702020207
Abstract: 为阐明不同生境对黄河三角洲滨海芦苇湿地土壤和植物碳（C）氮（N）磷（P）含量及生态化学计量特征的影响，选取新生湿地和退耕湿地两种湿地类型为研究对象，对土壤和植物体C、N、P含量及其化学计量特征进行研究。研究表明：1）退耕芦苇湿地土壤TC、TN的含量明显增加，TP的含量变化不大。2）新生湿地和退耕湿地土壤RC、N、P分别为42.6：1.6：1、71.2：2.0：1，RNP低于全球平均水平（13.1）和我国平均水平（5.2），土壤表现为N限制。新生湿地土壤剖面中，RCN和RCP变化剧烈；RNP值随深度的增加而减小；退耕湿地土壤RC、N、P值规律性较好，RCN随深度的增加而变大，RCP和RNP值随深度的增加而减小。3）新生湿地和退耕湿地中芦苇整株RCN、RCP和RNP平均值分别为78.2、1753、22.4；67.0、1539、23.0。开垦活动可以降低芦苇植物体RCN和RCP值，但由于芦苇植物体本身对RNP的约束性较高，对RNP值的影响不大，芦苇植株RNP约为23。以上结论可以为黄河三角洲国家级自然保护区正在进行的湿地保护与恢复工作提供借鉴和参考。 read more here.
Keywords: rcp rnp; rnp; rnp rcn; rcn rcp ... See more keywords
Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65742
Abstract: Ribonucleoprotein (RNP) granules are dynamic condensates enriched in regulatory RNA binding proteins (RBPs) and RNAs under tight spatiotemporal control. Extensive recent work has investigated the molecular principles underlying RNP granule assembly, unraveling that they form… read more here.
Keywords: tyramine induces; rnp; rnp granule; granule remodeling ... See more keywords