RNPS1 functions as an oncogenic splicing factor in cervical cancer cells
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DOI: 10.1002/iub.2686
Abstract: Numerous recent studies suggest that cancer‐specific splicing alteration is a critical contributor to the pathogenesis of cancer. RNA‐binding protein with serine‐rich domain 1, RNPS1, is an essential regulator of the splicing process. However, the defined… read more here.
Keywords: cervical cancer; rnps1; cancer; cell ... See more keywords
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration
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DOI: 10.1093/procel/pwac008
Abstract: Emerging evidence suggests that intron-detaining transcripts (IDTs) are a nucleus-detained and polyadenylated mRNA pool for cell to quickly and effectively respond to environmental stimuli and stress. However, the underlying mechanisms of detained intron (DI) splicing… read more here.
Keywords: contributes neurodegeneration; rnps1; molecular brake; spliceosome pausing ... See more keywords