Pseudomonas aeruginosa Nonphosphorylated AlgR Induces Ribonucleotide Reductase Expression under Oxidative Stress Infectious Conditions
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DOI: 10.1128/msystems.01005-22
Abstract: The emergence of multidrug-resistant bacteria is a serious problem worldwide. Pseudomonas aeruginosa is a pathogen that causes severe infections because it can form a biofilm that protects it from immune system mechanisms such as the… read more here.
Keywords: stress; pseudomonas aeruginosa; oxidative stress; rnrs ... See more keywords
A rapid and sensitive assay for quantifying the activity of both aerobic and anaerobic ribonucleotide reductases acting upon any or all substrates
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DOI: 10.1371/journal.pone.0269572
Abstract: Ribonucleotide reductases (RNRs) use radical-based chemistry to catalyze the conversion of all four ribonucleotides to deoxyribonucleotides. The ubiquitous nature of RNRs necessitates multiple RNR classes that differ from each other in terms of the phosphorylation… read more here.
Keywords: activity aerobic; rnrs; rnr; activity ... See more keywords
Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis.
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DOI: 10.2210/pdb6dqx/pdb
Abstract: Class I ribonucleotide reductases (RNRs) share a common mechanism of nucleotide reduction in a catalytic α subunit. All RNRs initiate catalysis with a thiyl radical, generated in class I enzymes by a metallocofactor in a… read more here.
Keywords: class; class ribonucleotide; structures class; rnrs ... See more keywords