Ro60/SSA levels are increased and promote the progression of pancreatic ductal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.124
Abstract: Ro60/SSA is a vital auto antigen that is targeted in Sjogren's syndrome and systemic lupus erythematosus (SLE). However, its role in solid cancers has rarely been reported. The present study investigated the expression and function… read more here.
Keywords: ro60 ssa; pancreatic ductal; ro60; ductal adenocarcinoma ... See more keywords
Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner.
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa414
Abstract: Noncoding Y RNAs are abundant in animal cells and present in many bacteria. These RNAs are bound and stabilized by Ro60, a ring-shaped protein that is a target of autoantibodies in patients with systemic lupus… read more here.
Keywords: protein; partner; ro60; regulate levels ... See more keywords