The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.113123
Abstract: Cyclic nucleotide phosphodiesterases (PDEs) are a superfamily of enzymes known to play a critical role in the indirect regulation of several intracellular metabolism pathways through the selective hydrolysis of the phosphodiester bonds of specific second… read more here.
Keywords: road designing; winding road; long winding; heart failure ... See more keywords