The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7
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DOI: 10.3389/fphar.2024.1374183
Abstract: The human voltage-gated sodium channel Nav1.7 is a widely proven target for analgesic drug studies. ProTx2, a 30-residue polypeptide from Peruvian green tarantula venom, shows high specificity to activity against human Nav1.7, suggesting its potential… read more here.
Keywords: protx2 subtype; human nav1; road evolution; nav1 ... See more keywords