HDAC inhibitor, MS-275, increases vascular permeability by suppressing Robo4 expression in endothelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Tissue Barriers"
DOI: 10.1080/21688370.2021.1911195
Abstract: ABSTRACT Roundabout guidance receptor 4 (Robo4) is an endothelial-specific membrane protein that suppresses pathological angiogenesis and vascular hyperpermeability by stabilizing endothelial cells. Robo4 suppresses severe systemic inflammation induced by pathogens and endotoxins and inhibits tumor… read more here.
Keywords: robo4 expression; expression; endothelial cells; hdac inhibitor ... See more keywords