RoBoT: a robust Bayesian hypothesis testing method for basket trials.
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DOI: 10.1093/biostatistics/kxaa005
Abstract: A basket trial in oncology encompasses multiple "baskets" that simultaneously assess one treatment in multiple cancer types or subtypes. It is well-recognized that hierarchical modeling methods, which adaptively borrow strength across baskets, can improve over… read more here.
Keywords: bayesian hypothesis; hypothesis testing; basket trials; robot robust ... See more keywords